Scientific Research &  Clinical Studies

IMPACT OF OXIDATIVE STRESS ON

MEMORY & COGNITION

 

 

Clinical Study: 

Oxidative stress predicts cognitive decline with aging in healthy adults: an observational study

Journal of Neuroinflammation 2018

Biomed Central Abstract: https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-017-1026-z

Comparative Study:

Evidence of increased oxidative damage in subjects with mild cognitive impairment

American Academy of Neurology 2005

Pub Med Abstract:  https://pubmed.ncbi.nlm.nih.gov/15824339/


Clinical Study:

Oxidative stress in Alzheimer's disease and mild cognitive impairment with high sensitivity and specificity

Journal of Alzheimer's disease  2013

Pub Med Abstract:  https://pubmed.ncbi.nlm.nih.gov/23076075/

Clinical Study:

Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease

Journal of Alzheimer's disease  2008

Pub Med Abstract: https://pubmed.ncbi.nlm.nih.gov/18780972/


Scientific Review:

Oxidative Stress in Cognitive and Epigenetic Aging: A Retrospective Glance

Frontiers in molecular neuroscience 2020

Pub Med Abstract: https://pubmed.ncbi.nlm.nih.gov/32256315/

Full article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093495/

Clinical Study:

Peripheral oxidative stress biomarkers in mild cognitive impairment and Alzheimer's disease

Journal of Alzheimer's disease 2011

Pub Med Abstract:  https://pubmed.ncbi.nlm.nih.gov/21593563/

Scientific Review: 

A Long Journey into Aging, Brain Aging, and Alzheimer's Disease Following the Oxidative Stress Tracks

Journal of Alzheimer's disease 2018

Pub Med Abstract: https://pubmed.ncbi.nlm.nih.gov/29562533/

Full Article:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870006/#idm140305906948656title


IMPACT OF ENDOGENOUS ANTIOXIDANTS ON

MEMORY &COGNITION

 

 

Clinical Study:

Brain glutathione levels--a novel biomarker for mild cognitive impairment and Alzheimer's disease

Biological Psychiatry Journal 2015

Pub Med Abstract: https://pubmed.ncbi.nlm.nih.gov/26003861/

Comparative Study:

Peripheral levels of glutathione and protein oxidation as markers in the development of Alzheimer's disease from Mild Cognitive Impairment

Free radical research 2008

Pub Med Abstract:  https://pubmed.ncbi.nlm.nih.gov/18297609/


Scientific Review:

Cognitive Improvement with Glutathione Supplement in Alzheimer's Disease: A Way Forward

Journal of Alzheimer's disease 2019

Pub Med Abstract: https://pubmed.ncbi.nlm.nih.gov/30776003/

Clinical Study:

Glutathione relates to neuropsychological functioning in mild cognitive impairment

Current opinion in psychiatry 2018

Pub Med Abstract:  https://pubmed.ncbi.nlm.nih.gov/23688577/


Clinical Trial:

Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease

Neurobiology of aging 2003

Pub Med Abstract:  https://pubmed.ncbi.nlm.nih.gov/12928050/

Scientific Review:

Promotion of cellular NAD(+) anabolism: therapeutic potential for oxidative stress in ageing and Alzheimer's disease

Neurotoxicity research (Journal) 2008

Pub Med Abstract: https://pubmed.ncbi.nlm.nih.gov/18522897/


Scientific Study:

Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function

Society for Free Radical Biology and Medicine (Journal) 2018

Pub Med Abstract: https://pubmed.ncbi.nlm.nih.gov/30107295/

Full Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092450/

Scientific Review:

Elevation of glutathione as a therapeutic strategy in Alzheimer disease

Biochimica et biophysica acta 2012

Pub Med Abstract: https://pubmed.ncbi.nlm.nih.gov/22015471/

Full  Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277671/


Scientific Review:

Evaluation of the Neuroprotective Potential of N-Acetylcysteine (NAC) for Prevention and Treatment of Cognitive Aging and Dementia

The journal of prevention of Alzheimer's disease 2017

Pub Med Abstract:  https://pubmed.ncbi.nlm.nih.gov/29182711/

Scientific Review:

Overview on the Effects of N-Acetylcysteine (NAC) in Neurodegenerative Diseases

Molecules : a Journal of synthetic chemistry and natural product chemistry 2018

Pub Med Abstract: https://pubmed.ncbi.nlm.nih.gov/30551603/

Full Article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320789/


Scientific  Review:

Improvement of cognitive function in schizophrenia with N-acetylcysteine (NAC)

Nutritional neuroscience (Journal) 2020

Pub Med Abstract: https://pubmed.ncbi.nlm.nih.gov/29847303/

Scientific Review:

Nicotinamide adenine dinucleotide (NAD+) and its related precursors for the treatment of Alzheimer's disease

Current opinion in psychiatry 2018

Pub Med Abstract:  https://pubmed.ncbi.nlm.nih.gov/29232252/